Atomic Homefront documents North St. Louis County, which is plagued by the negative consequences of radioactive waste that was secretly dumped into a neighborhood landfill and a suburban creek. This film profiles the people struggling to know the truth about what is poisoning them and how best to hold state and government agencies accountable.
Two groups of "mothers-turned-activists" are leading parallel causes: one to stop an uncontrolled, underground landfill fire from reaching Manhattan Project waste, and the other to determine if ionizing radiation poisoning is killing their children, parents, and friends.